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  • fluvoxamine
  • guanabenz
  • guanfacine
  • methyldopa

Zanaflex may also interact with the following medications:

  • acyclovir
  • alcohol
  • antihistamines
  • baclofen
  • barbiturates like phenobarbital
  • benzodiazepines
  • cimetidine
  • famotidine
  • female hormones, like estrogens or progestins and birth control pills
  • medicines for high blood pressure
  • medicines for irregular heartbeat
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  • medicines for sleep
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